This article will broach a number of Raman hyperspectral imaging applications that were developed in our laboratory, in order to demonstrate the significance of the technique. In the meanwhile, 70 alcohol has been used for even longer to disinfect wounds. These include Fluorescence spectroscopy for photoactivity, Particle Size analysis for composition and Raman microscopy for formulation investigation. Using holographic techniques we have structured the surface in a one step procedure (no wet nor photocuring processing ) along the X and Y directions. Laser processing provides a fast, non-contact and flexible method of modifying and patterning materials, from glasses to metals. In this article, we present how our Raman and X-Ray Fluorescence microscopies can be combined to shed some light on the origins of the universe. Raman microscopy is a technique which has proven highly valuable in a wide range of applications. The non destructive and in-situ analysis of pigments. This Application Note outlines three different kinds of spectroscopic tools being used for the characterization of sunscreens, and discusses the obtained results. The Raman effect allows fast, non-destructive chemical analysis of solids, powders, liquids, and gases. Recycling of damaged or abandoned fishing gear is one way of mitigating the issue, however the exact nature of the polymer must be known in order to identify the correct recycling stream. Metal oxides, in contrast to most metals, are wekk known to be easily distinguished by their characteristic Raman spectra; their presence can be detected on a scale of micrometers with a Raman microprobe. The use of TERS to reveal the defects density in the structure of CNTs is of interest for a better understanding of the electrical properties of the devices made with such nano-objects. The scientific community is increasingly interested in environmental contamination by plastics. In a quiet NYC neighborhood, a frustrated artist created forgeries of Americas Modernistic masters. We have performed a complete Raman polarized study of a single GaN nanowire using a confocal microscope together with a high resolution stage. With its non-destructive properties and high spatial resolution (< 1 m), Raman spectroscopy is thus a tool of choice for geological studies. Raman and resonance Raman spectroscopy have proven to be important research tools to investigate structure-function relationships in enzymes. Micro-machining, thin layers ablation, two-photon polymerization are just a few examples of what has already been demonstrated. Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles. The analysis of these multilayers is important to support, especially for safety and performances control. Do you have any questions or requests? nanoGPS Suite solution allows a colocalized combination of a variety of microscopy techniques, providing a full characterization of nanostructured materials and a precise superimposition of the results obtained. Less well known is that under certain conditions Raman spectroscopy can also be an effective method for quantitative analysis. Raman spectroscopy is a powerful and non-destructive characterization tool to study 2D materials. They often play an important role in electronic, material or biological applications; Quasi-2D structures, such as heterostructures, comprised of a stack of very thin layers, thus exhibiting new physical properties; 1D materials which include carbon nanotubes, nanowires, and nanorods; and. Identification and characterization of aeroallergens based on morphological and chemical features. There are many industries that need analytical instruments to control their products. Using the different microscopes instruments and being co-localized allows a comprehensive characterization of the sample and a precise superimposition of all the images. Its been more than a decade that Raman spectroscopy has been recognized as an efficient and powerful analytical tool in the field of Forensic Science. Raman spectroscopy is a very well suited technique to determine both Ge fraction and strain in SiGe layers and Si cap layers. Identification of contaminating microbes is an important public safety issue in many fields such as the control of food quality and the manufacture of pharmaceutical and cosmetic products. Raman and photoluminescence spectroscopy and imaging are used to examine the spatial variation of solid state structure and electronic character of two dimensional (2D) WS2 crystals. Characterization of protective mask fibers by Raman microscopy. Polymers, whether natural or synthetic, are found everywhere in our daily life from our clothes to buildings, as well as in packaging and cars. Vibrational spectroscopic characterization can take place all along the catalyst life from the control of the synthesis of the precursor to the cpntrol of the catalyst regeneration via the analysis of the surface reaction mechanism. Raman Investigation of Micro-organisms on a single cell level. Raman spectroscopy, combined to a temperature and humidity controller can mimic such harsh conditions and can be used to monitor the properties of the different ingre-dients and track their modifications induced by environmental changes. Here, you can read the many application notes and articles created by HORIBA application scientists. Laser diffraction and Raman microscopy were applied to highlight the benefits of combining two technologies for particle characterization. Transmission Raman Spectroscopy: review of applications. Investigating the atherosclerosis process by monitoring lipid deposits including cholesterol and free fatty acids. Graphene is a new nanomaterial which may partially replace silicon in microcircuits and computer chips in the future. Since the physical state can affect the pharmaceutical behavior of drug substances, it is important to know what controls crystallization, solid state reactions, phase stability, and solubility. Each mineral can be defined by its chemical composition and its crystalline structure, and sometimes can also contain fluid inclusions. Study of geological materials with Raman Spectroscopy. This proves the Raman spectrometer to be a very good tool to investigate the fine defects in the Diamond structure by Photoluminescence analysis. Valuable analysis tool for cosmetics and skin characterization. Raman spectroscopy turns out to be an ideally suited technique as its analyses are non-destructive and non-contact. Use this form to contact our specialists. In order to better understand its quality characteristics, fast reliable techniques that deliver the right property measures are needed. For hard carbon films, the spectra of amorphous and diamond-like carbons can be band-fit to separate the contributions of the "graphitic carbon" (G band) from the "disordered carbon" (D band). The PL signature of green and violet diamonds has also been recorded. Excipients and active pharmaceutical ingridients (APIs) can be analysed within seconds, and extensive Raman spectral libraries allow easy chemical identification. Encountered difficulties are linked to the samples themselves which are unique, in very small amount and need to be handled as little as possible. Multimodal spectroscopy techniques for nanostructured materials characterization. We apply three dimensional (3D) Raman imaging to understand and characterize the changes to the chemical bonding and crystalline structure as well as measure the volumetric structure of the waveguide segments. In the soap industry, many chemical reactions are involved for the preparation of the final product. Raman spectroscopy adapts to the different stages of life of these batteries, such as the characterisation of new materials for more flexible systems, failure analysis; but also more standard analysis of used material during charge/discharge process, including structural and electronic properties, and even robust, automated QC tests. The second part deals with the depth analysis of laminated films made of different polymer layers. Milk compounds characterization by optical spectroscopies and laser diffraction. These have lower sweetness than natural sugars. The presented examples demonstrate that Raman microspectroscopy can be successfully applied to the analysis and the identification of airborne pollen. Derivation of Physical Parameters from Raman Spectra of Hard Carbon Films. In vitro monitoring of time and dose dependent cytotoxicity of aminated nanoparticles using Raman spectroscopy. The prevalence of allergies in the world is between 30 and 40%. Nanomaterials are considered materials which have at least one of the three dimensions reduced down to nanometer scale. Optical Micro-spectroscopies on a Path to Identify the Source of Life. Lithium-ion batteries are thus of high interest. Here, we described a reverse engineering study on a bipolar plate from a commercial vehicle using GD-OES and Raman spectroscopy. Combined Raman and Photoluminescence Imaging of 2D WS2. Development of an optimal filter substrate for the identification of small microplastic particles in food by micro-Raman spectroscopy. Application Notes FLUO, RA, PSA 02: Spectroscopic methods for sunscreens characterization RA PSA 01: Particle characterization by optical spectroscopies and laser diffraction RA69: Soap compound investigation by Raman mapping Publications " Raman Spectroscopy and Polymorphism. Read application notes and articles, and get new perspectives on your lab research. Spectroscopy, 34 (3):10-21 Raman spectroscopic method for semen identification: azoospermia. The present study of mediaeval pigments using micro-Raman spectroscopy provides important information on the inorganic and organic type of pigments used in the wall paintings in the remains of the church in Skopsko Kale (Skopje Fortress). Developed on the same platform, the LabRAM Odyssey is now more user friendly and offers new functionalities, advanced . Polymerization process monitoring The objective of the measurements is to identify the unknown components and their respective dispersion within pharmaceutical tabs by Raman and FT-IR microspectrometry. Here, you can read the many application notes and articles created by HORIBA application scientists. Many challenges remain before the promise of 2D materials is realized in the form of practical nano-devices. The application note explains how the Raman Spectroscopy can be helpful in the analysis of cathodes and anodes in Li-ion batteries. The correlation between knowledge about structure with physical and chemical properties about the tubes make the technique extremely powerful to control the quality of the SWCNTs for specific applications. Its non-invasive behavior, and its high molecular sensitivity make it one of the preferred label-free analytical techniques to characterize materials such as skin and cosmetic products. Here, we use Raman microscopy by cross-section analysis and confocal depth profiling to investigate the chemical composition of two multilayers films. In this application note, we showed how optical spectroscopies and laser diffraction can help for food compounds characterization, especially on a specific product, i.e. These types of masks are distinguished, in particular, by their different efficiencies linked to their filtration capacity. Confocal Raman microspectrometry imaging combined with chemometric methods. PDF Raman Structural characterization of WS flakes Application Raman by To overcome this major public issue, innovative analytical characterization tools such as microRaman spectroscopy are required. Use this form to contact our specialists. application notes and articles, and get new perspectives on your lab research. Raman Microscopy Applied to Polymer Characterization: An Overview. Analysis of microplastics in hand sanitizers using ParticleFinder. Raman Application Corner - HORIBA But, to remain efficient, the alcohol concentration of these products must not be below a defined threshold and must be controlled. Raman Spectroscopy has many useful properties which can be explored and exploited in the analysis of pharmaceutical formulations. Raman Spectroscopy did him in. Characterization of MoS2 Flakes using TEOS. A Depth Profile of Polymer Protection Covers Using Raman and UFS-GDOES. It becomes so easy to characterize the exact type of polymers using a state-of-the art Raman microscope as the HORIBA LabRAM SoleilTM. Evaluating molecular evolution of kerogen by Raman spectroscopy: Correlation with optical microscopy and rock-eval pyrolysis. Soap compound investigation by Raman mapping. The Raman spectra of elemental carbon materials are known to be sensitive to polymorphy. However, Raman is a weak phenomenon, and its sensitivity is not always ideal, particularly when analysing what are often relatively low concentration of intracellular components. Characterization will include structural and electronic properties, or failure analysis, which is very useful in the quality control process, or state comparisons at different periods of time for stability studies. Natural rocks composing the Earth are complex. Coloured Diamond Defect Idenditication by Raman Diffusion and Photoluminescence. Recent developments in Raman instrumentation have made the technique easier to use, more compact, and more affordable. As technology evolves at a high rate of speed, it requires more reliable, efficient and powerful energy sources. Raman Analysis of Sperm Nuclear DNA Integrity. Pulsed RF Glow Discharge Optical Emission Spectrometry, coupled with the Ultra Fast Sputtering system, offers the Ultra Fast Elemental Depth Profiling of plastic thin films Polymer Mobile Screen Protection Covers. Smart nanostructured materials require a comprehensive understanding of their morphology, elemental and chemical composition. The analyses revealed that the plate had an amorphous carbon coating on a titanium base plate. The non destructive and in-situ identification of different black inks. Bipolar plates are key components of proton exchange membrane fuel cells they notably distribute fuel gas and air and conduct electricity. Quantitative Analysis Using Raman Spectroscopy in Pharmaceutical Applications. Indeed, it is a non-destructive, non-contact and non-contaminating technique which does not need any sample preparation. The high spatial resolution of our Raman confocal instrument together with a piezoelectric stage demonstrates unambiguously the possibility to image the optical properties of nano-objects with a resolution better than 200 nm keeping the fill advantage of the polarization control under a confocal microscope. Their dimensions range from a few nanometers to tens of micrometers and their atmospheric life time can be as long as several weeks so that they can impact the global as well as the regional climates. PISCATAWAY, NJ HORIBA Scientific, world leader in Raman microscopy, announces the new LabRAM Odyssey, a fully automated and remotely controllable system. Proton Exchange Membrane Fuel Cell Bipolar Plate Analyses by GD-OES and Raman. Transmission Raman spectroscopy: review of applications, Concentration profile measurements in polymeric coatings during drying by means of Inverse-Micro-Raman-Spectroscopy (IMRS), Raman imaging of holographic gratings inscribed on polymer thin films. Upon deconvolution, the TEPL signal is even capable of revealing local inhomogeneities within a MoS2 flake of 100 nm size. It has the advantage of being not only simple and inexpensive, but also allows for re-cycling used material. PDF Solid State Application Note 03 - static.horiba.com

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