reasons not to get the meningitis vaccine
There are 2 types of meningococcal vaccines used in the United States: CDC recommends meningococcal vaccination for all preteens and teens. In 2005, a vaccine called MCV4 that produced more reliable immunity in children was introduced. States With Religious and Philosophical Exemptions From School A small percentage of people who receive the vaccine develop a fever. Covid Religious Exemption - Examples, PDF | Examples Should you and your family get the meningitis vaccination? Mild problems following MenACWY vaccination can include: If these problems occur, they usually last for 1 or 2 days. In the United States, the most common are Streptococcus pneumoniae, group B streptococcus, Neisseria meningitides, Haemophilus influenzae, and Listeria monocytogenes. Pale blotchy skin with spots or a rash - don't wait for a rash before seeking help, as this can be a late sign, or may not appear at all If you notice any meningitis symptoms, call your GP or go to A&E immediately. Texas Minimum State Vaccine Requirements for College Entry Book a consultation today. Teens who get their first dose after age 16 won't need a . NCSL's experts are here to answer your questions and give you unbiased, comprehensive information as soon as you need it . In some cases, an additional vaccine during teenage, college, or even adult years might be required. Most people who get a meningococcal vaccine do not have any serious problems with it. Since children, teens, and college-age young adults are the populations most at risk for meningitis, this vaccine was not an ideal way to combat meningitis. Write a letter that explains their reasons for refusing vaccines. Meningococcal disease usually presents clinically as meningitis (about 50% of cases), bacteremia (30% of cases), or bacteremic pneumonia (15% of cases). Last medically reviewed on February 27, 2022, Most forms of meningitis are infectious, such as viral and bacterial, and can spread from person to person. What Are the Rules on Vaccine Exemptions? - WebMD 24 reasons to not vaccinate your kid - KevinMD.com Most health insurance plans cover routine vaccinations. All of those things are creating an environment where you can have an outbreak situation., Wukovits agrees. However, the second vaccination, MenB, is relatively new. Learn how COVID-19 could lead to meningitis in rare cases and what it may mean for your treatment and outlook. Can poor sleep impact your weight loss goals? All rights reserved. The meningitis vaccine, also known as the MenACWY vaccine, protects against four of the meningococcal strains of bacteria that cause meningitis - A, C, W and Y. I have read and I understand the Risks and Benefits of Meningococcal Vaccination information. Try our Symptom Checker Got any other symptoms? Possible side effects of the MenACWY vaccine include: Possible side effects of the MenB vaccine include: Vaccines are effective protection against meningitis, but they dont prevent 100% of all cases. GOP lawmaker wants to suspend parts of new Wisconsin vaccination policy Your age and risk for meningitis influence which vaccine is right for you. Even if you have the meningitis jab, "it doesn't cover all strains of meningitis nor is every vaccine 100% effective," says Donovan. Each new vaccine intended for . Shown here are pain receptors (in red) in the brain's protective layers, known as meninges. The protective effects of the MenACWY vaccine decrease after 5 years. That puts the current rate of disease at a historic low. We take your privacy seriously. Placebos Used in Vaccine Trials Do Not Please Everyone Learn about the effects of meningitis here. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Meningitis is a disease that can be caused by different viruses and bacteria. Need a meningitis (ACWY) vaccination? A vaccine can be the first of its kind against a disease or it may be a challenger to the throne. The MenB vaccine always requires at least two doses, but it doesnt require a booster. However, the MenB shot isnt necessary for most college students. Meningococcal Vaccination: What Everyone Should Know | CDC Get a signature from a local health department official. While its approved for anyone between the ages of 10 and 25, it hasnt yet been added to the standard vaccination schedule. Not all religious beliefs would want their people to take the . Healthy adults won't require another dose of this vaccine. Global Meningitis Vaccine Market Research Report 2023, Size, CAGR Value If you have concerns about vaccine safety, get advice from a medical professional. With any medicine, including vaccines, there is a chance of side effects. People can pay for meningococcal vaccines in several ways: Most private health insurance plans cover these vaccines. You can learn more about how we ensure our content is accurate and current by reading our. Although some people may experience pain at the injection site or even faint after a vaccination, serious side effects, such as severe allergic reactions, serious injury, or death, are extremely rare. The CDC recommends that people have a vaccination against meningitis. Texas Medical Association: "Texas Immunization Requirements. ", National Conference of State Legislatures: "States with religious and philosophical exemptions from school immunization requirements. Guidelines suggest that all children receive the MenACWY vaccine at 1112 and the booster at 16. The meningococcal conjugate vaccine covers some of the most common forms of bacterial meningitis, a devastating disease that almost always requires hospitalization and can cause permanent. CDC: "Frequently Asked Questions about Measles in the U.S.," "Immunization," "Measles Cases and Outbreaks," "Mumps Cases and Outbreaks," "State School and Childcare Vaccination Laws," "Vaccination coverage among children aged 19 - 35 months -- United States, 2017," "What is an Exemption and What Does it Mean? "One in ten people in the general population carry these bacteria harmlessly in the back of their nose and throat. Anyone who thinks they might be at high risk of getting the disease should consult their doctors about getting a vaccine for themselves or their children. Vomiting. Meningitis Vaccines and Immunization Tips - WebMD Your Guide to Salmonella Meningitis and How to Spot It, Group B Streptococcal (GBS) Meningitis: Symptoms, Treatment, Outlook, and More, Everything You Need to Know About Mollarets Meningitis. The CDC recommends that children receive their first MenACWY vaccine between the ages of 11 and 12. Some parents are concerned about vaccine safety. Here's Why Childhood Vaccines Aren't Really Dangerous 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. This article explores the meningitis vaccine, who it is for, and its risks and possible side effects. Those who have their first dose between the ages of 13-15 should get a booster dose between the ages of 16-18. Healthcare experts recommend the MenACWY vaccine for preteens ages 1112, a booster when they turn 16, and teens ages 1118 if they are not vaccinated. Doctors divided on meningitis B vaccine - San Diego Union-Tribune Needles are a common fear, and many people worry about the possible side effects of vaccines. One of the bacteria which causes meningitis is called Neisseria meningitidis, also known as the meningococcus. It is most often due to bacteria or a virus.. At first, symptoms can appear flu-like in nature, like headaches, body aches, and fever. Many of these concerns have been debunked, such as a theory that vaccines cause autism. Covid vaccine: 10 reasons why young, healthy people should get - CNN Many people are aware that meningitis is a vaccine-preventable disease. Thank you for taking the time to confirm your preferences. N. meningitidis colonizes mucosal surfaces of the nasopharynx and is transmitted through direct contact with large-droplet respiratory tract secretions from patients or asymptomatic carriers. According to the National Meningitis Association (NMA), around 6001,000 in the United States people contract meningococcal disease, which is a type of bacterial meningitis, each year, and 1015% of these people die as a result. Experts are currently worried about an increase in cases associated with a particularly aggressive MenW strain, called ST-11 - in 2009/10 there were only 22 cases in England, but this went up to 210 cases in 2015/16. Reason to Get a Vaccine. The meningitis vaccine is safe. CDC first recommended preteens and teens get a MenACWY vaccine in 2005. School Vaccines and Updates | Georgia Department of Public Health NYS Immunization Requirements and Exemptions - MVCC There are two versions of the meningitis vaccine available. The MenB vaccines are recommended in people ages 10 and older who have certain risk factors. It seems the best cure really is prevention, so start thinking about getting the meningitis vaccine before going to uni. In some cases, a MenB vaccine can be given at the same time. Meningitis vaccines: What parents need to know - Harvard Health However, this early meningitis vaccine was most effective in adults. One reason was that some doctors began writing medical exemptions for parents who had personal objections to vaccines. Safe affordable vaccines are the most effective way to deliver long-lasting protection. Therefore, vaccines for children and teens are regularly available at. Meningitis can be caused by many kinds of bacteria and viruses. In 1855, Massachusetts became the first state to require children to get vaccinated to attend school. What You Need to Know About Meningitis Vaccines | U.S. News Association between Meningococcal Meningitis and Santa Ana Winds in Like many childhood vaccines, the COVID-19 vaccines can cause minor side effects that usually go away after a day or two. Available data suggest that protection from MenACWY vaccines decreases in many teens within 5 years. However, everyone at higher risk of contracting meningococcal disease should get the vaccine. If youre uninsured and need vaccines for your child, the federally funded program Vaccines for Children (VFC) can help get them the care they need and meet any requirements for their school. Its recommended that children receive the vaccine when they are 11 or 12 years old, followed by a booster at age 16. While anyone can get meningococcal disease, the Centers for Disease Control and Prevention (CDC) indicate that babies under 1 year and people aged 1623 years are most likely to contract it. Vaccination is recommended only for certain populations deemed at high risk for . Ask the Experts: Meningococcal B Vaccines - immunize.org 44 out of 747 umrah pilgrims are late to get vaccine eventhough this vaccine must be given no later than 14 days before the . When someone who is sick comes into one of these areas, outbreaks can happen. Other symptoms of meningitis also include confusion, stiff neck, seizures, sleepiness, and sensitivity to light. At first, symptoms can appear flu-like in nature. If you think you have meningitis, go to the ER immediately. Meningococcal | HHS.gov 4 There are two different manufacturers with two different dosing techniques (one requiring two injections and the other requiring three), which can further complicate the vaccination process for some patients. As horrifying as it is to think that any child might go needlessly unprotected, expanding vaccination to older children - who are at much smaller risk - could make such treatments so expensive. Is exercise more effective than medication for depression and anxiety? Having the meningitis vaccine doesn't just protect you. Meningitis B vaccines, like Bexero and Trumenba, are made up of three proteins found on the surface of one subtype of the Neisseria meningitidis . CDC studies have talked about dorm settings, where youre in close contact similar to military barracks, as being a risk. Nyquist explained. Although exemptions vary from state to state, all school immunization laws grant exemptions to children for medical reasons. There are two meningitis vaccines available in the US, and both are proven safe. "What we have found, therefore, is that vaccinating teens against a strain of meningitis bacteria causes rates of infection for that strain to drop in everyone," says Wright. You can review and change the way we collect information below. People who have a moderate or severe illness should probably wait until they recover. Learn more about common side effects of vaccinations here. Is There a Vaccine For Meningitis? - GoodRx It was released for use in the United States in 2014. But we need all healthcare providers to talk to their young patients about the MenB vaccine so patients and parents can make an informed decision. Yes. Meningitis is very rare, so data on vaccine effectiveness is limited. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Last medically reviewed on September 2, 2022. Scarily, one in seven teenagers infected with MenW don't survive. Vaccination with MenACWY is recommended: when kids are 11 or 12 years old, with a booster given at age 16. for teens 13-18 years old who haven't been vaccinated yet. The MenACWY vaccine used today was introduced in 2010. They are rare cases, but its not a rare case when youre the one.. The meninges are densely innervated by nociceptive sensory neurons that mediate pain and headache. The UK was the first group of countries in the world to introduce a MenB vaccine into its national programme using the Bexsero vaccine. Vaccines help children avoid serious diseases. Part of the reason that meningitis rates are so low in the United States is due to the high vaccination rates. One reason people are vaccine-hesitant is that we see autism but we no longer see . Mollaret's meningitis is a rare form of meningitis often caused by the HSV-2 virus. Its typically included in the regular vaccine schedule and is given to children around age 11 with a booster recommended around age 16. Thanks to vaccines, there are fewer cases of meningococcal disease in the United States than ever before. This fact sheet answers general questions about meningococcal vaccines for preteens and teens. Talk to your or your childs doctor about what is best for your specific situation. Meningitis is an infection and inflammation of the fluid and membranes surrounding the brain and spinal cord. "To protect yourself and your friends it's still important to be aware of symptoms of meningitis.". Among all 11- to 23-year-olds in the U.S., between 50 and 60 cases are reported annually, with five to 10 deaths . Research suggests that the protective antibodies your body makes after a dose of the MenB vaccine decrease after 1 to 2 years. Texas Immunization Exemptions | Texas DSHS And, as her parent, you feel that your main job is to keep her comfortable rather than safe. DSHS recognizes, however, that for a small number of people, there may be valid medical reasons for which they cannot receive certain vaccines. If you have ever had a life-threatening allergic reaction after a previous dose of MenACWY or MenB vaccine, do not get another dose of that type of vaccine. 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There are 2 types of meningococcal vaccines used in the United States: CDC recommends meningococcal vaccination for all preteens and teens. In 2005, a vaccine called MCV4 that produced more reliable immunity in children was introduced. States With Religious and Philosophical Exemptions From School A small percentage of people who receive the vaccine develop a fever. Covid Religious Exemption - Examples, PDF | Examples Should you and your family get the meningitis vaccination? Mild problems following MenACWY vaccination can include: If these problems occur, they usually last for 1 or 2 days. In the United States, the most common are Streptococcus pneumoniae, group B streptococcus, Neisseria meningitides, Haemophilus influenzae, and Listeria monocytogenes. Pale blotchy skin with spots or a rash - don't wait for a rash before seeking help, as this can be a late sign, or may not appear at all If you notice any meningitis symptoms, call your GP or go to A&E immediately. Texas Minimum State Vaccine Requirements for College Entry Book a consultation today. Teens who get their first dose after age 16 won't need a . NCSL's experts are here to answer your questions and give you unbiased, comprehensive information as soon as you need it . In some cases, an additional vaccine during teenage, college, or even adult years might be required. Most people who get a meningococcal vaccine do not have any serious problems with it. Since children, teens, and college-age young adults are the populations most at risk for meningitis, this vaccine was not an ideal way to combat meningitis. Write a letter that explains their reasons for refusing vaccines. Meningococcal disease usually presents clinically as meningitis (about 50% of cases), bacteremia (30% of cases), or bacteremic pneumonia (15% of cases). Last medically reviewed on February 27, 2022, Most forms of meningitis are infectious, such as viral and bacterial, and can spread from person to person. What Are the Rules on Vaccine Exemptions? - WebMD 24 reasons to not vaccinate your kid - KevinMD.com Most health insurance plans cover routine vaccinations. All of those things are creating an environment where you can have an outbreak situation., Wukovits agrees. However, the second vaccination, MenB, is relatively new. Learn how COVID-19 could lead to meningitis in rare cases and what it may mean for your treatment and outlook. Can poor sleep impact your weight loss goals? All rights reserved. The meningitis vaccine, also known as the MenACWY vaccine, protects against four of the meningococcal strains of bacteria that cause meningitis - A, C, W and Y. I have read and I understand the Risks and Benefits of Meningococcal Vaccination information. Try our Symptom Checker Got any other symptoms? Possible side effects of the MenACWY vaccine include: Possible side effects of the MenB vaccine include: Vaccines are effective protection against meningitis, but they dont prevent 100% of all cases. GOP lawmaker wants to suspend parts of new Wisconsin vaccination policy Your age and risk for meningitis influence which vaccine is right for you. Even if you have the meningitis jab, "it doesn't cover all strains of meningitis nor is every vaccine 100% effective," says Donovan. Each new vaccine intended for . Shown here are pain receptors (in red) in the brain's protective layers, known as meninges. The protective effects of the MenACWY vaccine decrease after 5 years. That puts the current rate of disease at a historic low. We take your privacy seriously. Placebos Used in Vaccine Trials Do Not Please Everyone Learn about the effects of meningitis here. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Meningitis is a disease that can be caused by different viruses and bacteria. Need a meningitis (ACWY) vaccination? A vaccine can be the first of its kind against a disease or it may be a challenger to the throne. The MenB vaccine always requires at least two doses, but it doesnt require a booster. However, the MenB shot isnt necessary for most college students. Meningococcal Vaccination: What Everyone Should Know | CDC Get a signature from a local health department official. While its approved for anyone between the ages of 10 and 25, it hasnt yet been added to the standard vaccination schedule. Not all religious beliefs would want their people to take the . Healthy adults won't require another dose of this vaccine. Global Meningitis Vaccine Market Research Report 2023, Size, CAGR Value If you have concerns about vaccine safety, get advice from a medical professional. With any medicine, including vaccines, there is a chance of side effects. People can pay for meningococcal vaccines in several ways: Most private health insurance plans cover these vaccines. You can learn more about how we ensure our content is accurate and current by reading our. Although some people may experience pain at the injection site or even faint after a vaccination, serious side effects, such as severe allergic reactions, serious injury, or death, are extremely rare. The CDC recommends that people have a vaccination against meningitis. Texas Medical Association: "Texas Immunization Requirements. ", National Conference of State Legislatures: "States with religious and philosophical exemptions from school immunization requirements. Guidelines suggest that all children receive the MenACWY vaccine at 1112 and the booster at 16. The meningococcal conjugate vaccine covers some of the most common forms of bacterial meningitis, a devastating disease that almost always requires hospitalization and can cause permanent. CDC: "Frequently Asked Questions about Measles in the U.S.," "Immunization," "Measles Cases and Outbreaks," "Mumps Cases and Outbreaks," "State School and Childcare Vaccination Laws," "Vaccination coverage among children aged 19 - 35 months -- United States, 2017," "What is an Exemption and What Does it Mean? "One in ten people in the general population carry these bacteria harmlessly in the back of their nose and throat. Anyone who thinks they might be at high risk of getting the disease should consult their doctors about getting a vaccine for themselves or their children. Vomiting. Meningitis Vaccines and Immunization Tips - WebMD Your Guide to Salmonella Meningitis and How to Spot It, Group B Streptococcal (GBS) Meningitis: Symptoms, Treatment, Outlook, and More, Everything You Need to Know About Mollarets Meningitis. The CDC recommends that children receive their first MenACWY vaccine between the ages of 11 and 12. Some parents are concerned about vaccine safety. Here's Why Childhood Vaccines Aren't Really Dangerous 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. This article explores the meningitis vaccine, who it is for, and its risks and possible side effects. Those who have their first dose between the ages of 13-15 should get a booster dose between the ages of 16-18. Healthcare experts recommend the MenACWY vaccine for preteens ages 1112, a booster when they turn 16, and teens ages 1118 if they are not vaccinated. Doctors divided on meningitis B vaccine - San Diego Union-Tribune Needles are a common fear, and many people worry about the possible side effects of vaccines. One of the bacteria which causes meningitis is called Neisseria meningitidis, also known as the meningococcus. It is most often due to bacteria or a virus.. At first, symptoms can appear flu-like in nature, like headaches, body aches, and fever. Many of these concerns have been debunked, such as a theory that vaccines cause autism. Covid vaccine: 10 reasons why young, healthy people should get - CNN Many people are aware that meningitis is a vaccine-preventable disease. Thank you for taking the time to confirm your preferences. N. meningitidis colonizes mucosal surfaces of the nasopharynx and is transmitted through direct contact with large-droplet respiratory tract secretions from patients or asymptomatic carriers. According to the National Meningitis Association (NMA), around 6001,000 in the United States people contract meningococcal disease, which is a type of bacterial meningitis, each year, and 1015% of these people die as a result. Experts are currently worried about an increase in cases associated with a particularly aggressive MenW strain, called ST-11 - in 2009/10 there were only 22 cases in England, but this went up to 210 cases in 2015/16. Reason to Get a Vaccine. The meningitis vaccine is safe. CDC first recommended preteens and teens get a MenACWY vaccine in 2005. School Vaccines and Updates | Georgia Department of Public Health NYS Immunization Requirements and Exemptions - MVCC There are two versions of the meningitis vaccine available. The MenB vaccines are recommended in people ages 10 and older who have certain risk factors. It seems the best cure really is prevention, so start thinking about getting the meningitis vaccine before going to uni. In some cases, a MenB vaccine can be given at the same time. Meningitis vaccines: What parents need to know - Harvard Health However, this early meningitis vaccine was most effective in adults. One reason was that some doctors began writing medical exemptions for parents who had personal objections to vaccines. Safe affordable vaccines are the most effective way to deliver long-lasting protection. Therefore, vaccines for children and teens are regularly available at. Meningitis can be caused by many kinds of bacteria and viruses. In 1855, Massachusetts became the first state to require children to get vaccinated to attend school. What You Need to Know About Meningitis Vaccines | U.S. News Association between Meningococcal Meningitis and Santa Ana Winds in Like many childhood vaccines, the COVID-19 vaccines can cause minor side effects that usually go away after a day or two. Available data suggest that protection from MenACWY vaccines decreases in many teens within 5 years. However, everyone at higher risk of contracting meningococcal disease should get the vaccine. If youre uninsured and need vaccines for your child, the federally funded program Vaccines for Children (VFC) can help get them the care they need and meet any requirements for their school. Its recommended that children receive the vaccine when they are 11 or 12 years old, followed by a booster at age 16. While anyone can get meningococcal disease, the Centers for Disease Control and Prevention (CDC) indicate that babies under 1 year and people aged 1623 years are most likely to contract it. Vaccination is recommended only for certain populations deemed at high risk for . Ask the Experts: Meningococcal B Vaccines - immunize.org 44 out of 747 umrah pilgrims are late to get vaccine eventhough this vaccine must be given no later than 14 days before the . When someone who is sick comes into one of these areas, outbreaks can happen. Other symptoms of meningitis also include confusion, stiff neck, seizures, sleepiness, and sensitivity to light. At first, symptoms can appear flu-like in nature. If you think you have meningitis, go to the ER immediately. Meningococcal | HHS.gov 4 There are two different manufacturers with two different dosing techniques (one requiring two injections and the other requiring three), which can further complicate the vaccination process for some patients. As horrifying as it is to think that any child might go needlessly unprotected, expanding vaccination to older children - who are at much smaller risk - could make such treatments so expensive. Is exercise more effective than medication for depression and anxiety? Having the meningitis vaccine doesn't just protect you. Meningitis B vaccines, like Bexero and Trumenba, are made up of three proteins found on the surface of one subtype of the Neisseria meningitidis . CDC studies have talked about dorm settings, where youre in close contact similar to military barracks, as being a risk. Nyquist explained. Although exemptions vary from state to state, all school immunization laws grant exemptions to children for medical reasons. There are two meningitis vaccines available in the US, and both are proven safe. "What we have found, therefore, is that vaccinating teens against a strain of meningitis bacteria causes rates of infection for that strain to drop in everyone," says Wright. You can review and change the way we collect information below. People who have a moderate or severe illness should probably wait until they recover. Learn more about common side effects of vaccinations here. Is There a Vaccine For Meningitis? - GoodRx It was released for use in the United States in 2014. But we need all healthcare providers to talk to their young patients about the MenB vaccine so patients and parents can make an informed decision. Yes. Meningitis is very rare, so data on vaccine effectiveness is limited. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Last medically reviewed on September 2, 2022. Scarily, one in seven teenagers infected with MenW don't survive. Vaccination with MenACWY is recommended: when kids are 11 or 12 years old, with a booster given at age 16. for teens 13-18 years old who haven't been vaccinated yet. The MenACWY vaccine used today was introduced in 2010. They are rare cases, but its not a rare case when youre the one.. The meninges are densely innervated by nociceptive sensory neurons that mediate pain and headache. The UK was the first group of countries in the world to introduce a MenB vaccine into its national programme using the Bexsero vaccine. Vaccines help children avoid serious diseases. Part of the reason that meningitis rates are so low in the United States is due to the high vaccination rates. One reason people are vaccine-hesitant is that we see autism but we no longer see . Mollaret's meningitis is a rare form of meningitis often caused by the HSV-2 virus. Its typically included in the regular vaccine schedule and is given to children around age 11 with a booster recommended around age 16. Thanks to vaccines, there are fewer cases of meningococcal disease in the United States than ever before. This fact sheet answers general questions about meningococcal vaccines for preteens and teens. Talk to your or your childs doctor about what is best for your specific situation. Meningitis is an infection and inflammation of the fluid and membranes surrounding the brain and spinal cord. "To protect yourself and your friends it's still important to be aware of symptoms of meningitis.". Among all 11- to 23-year-olds in the U.S., between 50 and 60 cases are reported annually, with five to 10 deaths . Research suggests that the protective antibodies your body makes after a dose of the MenB vaccine decrease after 1 to 2 years. Texas Immunization Exemptions | Texas DSHS And, as her parent, you feel that your main job is to keep her comfortable rather than safe. DSHS recognizes, however, that for a small number of people, there may be valid medical reasons for which they cannot receive certain vaccines. If you have ever had a life-threatening allergic reaction after a previous dose of MenACWY or MenB vaccine, do not get another dose of that type of vaccine.

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reasons not to get the meningitis vaccine